Cholesterol-X

• 60 Vegetarian Capsules

This is an exclusive formula that features a proprietary blend of policosanol from sugar cane extract. It also has a revolutionary magnesium amino acid chelate and mineral complex produced by an innovative patented process which is designed to give maximum absorption [1]. Each capsule provides 10 mg of policosanol and 100 mg of elemental magnesium. An impressive body of research suggests that both policosanol and magnesium may provide significant cardio-protective benefits. This formula lowers cholesterol, promotes healthy fat metabolism, moderates triglyceride support, facilitates muscle relaxation and supports platelet function, nerve transmission, and enhances antioxidant protection for cardiovascular health.

Policosanol

The powerful, beneficial effect of policosanol on blood lipids has been extensively studied in both humans and animals, and its effectiveness has been compared to several commonly prescribed lipid-modifying agents [2,3]. Additionally, policosanol has been shown to promote binding, uptake, and degradation of low-density lipoproteins (LDL). Studies suggests that policosanol at a dose range of 5 to 20 mg per day is effective for promoting healthy blood lipid synthesis and metabolism [3,4].

Magnesium and Cardiovascular Health

Magnesium is a vital nutrient that is essential to the proper functioning of the entire cardiovascular system [5]. It is necessary for nearly every major physiologic process in the body and plays an important role in the regulation of muscle contraction, heartbeat, nerve transmission, and vascular tone. Magnesium deficiency is widely recognized as a contributing factor in the etiology of heart disease and commonly occurs with conditions such as arrhythmia, hypertension, myocardial infarction, and mitral valve prolapse. In experimental studies, low plasma levels of magnesium have been shown to accelerate atherogenesis by increasing concentrations of LDL and peroxidized lipoproteins, and by promoting inflammation [6,7]. Additionally, magnesium deficiency is known to contribute to an imbalance of electrolytes, such as Na+, K+, and Ca2+, which can negatively affect myocardial function. Magnesium supplementation has been shown to benefit patients with cardiac arrhythmia and hypertension, improve endothelial function in patients with coronary artery disease, and increase the survival rate of patients with congestive heart failure.

References

1. Arruzazabala ML, Mas R, Molina V, et al. Effect of policosanol on platelet aggregation in type II hypercholesterolemic patients. Int J Tissue React 1998;20(4):119-24
2. Arruzazabala ML, Molina V, Mas R, Fernandez L, et al. Antiplatelet effects of policosanol (20 and 40 mg/day) in healthy volunteers and dyslipidaemic patients. Clin Exp Pharmacol Physiol 2002 Oct;29(10):891-7
3. Batista J, Stusser R, Saez F, et al. Effect of policosanol on hyperlipidemia and coronary heart disease in middle-aged patients. A 14-month study. Int J Clin Pharmacol Ther 1996;34(3):134-37
4. Castano G, Mas R, Fernandez L, Gamez, Illnait J. Effects of policosanol and lovastatin in patients with intermittent claudication: a double-blind comparative pilot study. Angiology 2003 Jan;54(1):25-38
5. Chakraborti S, Chakraborti T, Mandal M, Mandal A, Das S, Ghosh S. Protective role of magnesium in cardiovascular diseases: a review. Mol Cell Biochem 2002 Sep;238(1-2):163-79
6. Maier JA. Low magnesium and atherosclerosis: an evidence-based link. Mol Aspects Med 2003 Feb 6;24(1-3):137-46
7. Zhang Y, Davies LR, Martin SM, Bawaney Im, Buettner GR, Kerber RE. Magnesium reduces free radical concentration and preserves left ventricular function after direct current shocks. Resuscitation 2003 Feb;56(2):199-206